NANOPARTICLES AS A BIORECOGNITION PLATFORM IN COMBINATION WITH LA-ICP-MS

1,2 VLCNOVSKA Marcela
Co-authors:
3 STOSSOVA Aneta 3 TVRDONOVA Michaela 2 POLANSKA Hana 1,4 VACULOVICOVA Marketa 3 VACULOVIC Tomas 2 MASARIK Michal
Institutions:
1 Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, 613 00 Brno, Czech Republic, EU, marcelavlcnovska@seznam.cz
2 Department of Pathological Physiology Masaryk University Kamenice 753/5, 625 00 Brno, Czech Republic, EU
3 Department of Chemistry Masaryk University Kamenice 753/5, 625 00 Brno, Czech Republic, EU
4 Central European Institute of Technology Brno University of Technology Purkynova 123, 612 00 Brno, Czech Republic, EU
Conference:
11th International Conference on Nanomaterials - Research & Application, Hotel Voronez I, Brno, Czech Republic, EU, October 16th - 18th 2019
Proceedings:
Proceedings 11th International Conference on Nanomaterials - Research & Application
Pages:
434-437
ISBN:
978-80-87294-95-6
ISSN:
2694-930X
Published:
1st April 2020
Proceedings of the conference have been sent to Web of Science and Scopus for evaluation and potential indexing.
Metrics:
41 views / 12 downloads
Abstract

Metal nanoparticles proved to be effective signaling tags in combination with laser ablation followed by inductively coupled plasma mass spectrometric detection. The surface may be suitably modified by various biorecognition elements such as antibodies or aptamers. Moreover, molecularly imprinted polymers can be prepared on their surface. In this study, the biorecognition capabilities of nanoparticles functionalized by antibodies and molecularly imprinted polymers were compared.

Keywords: Nanoparticles, LA-ICP-MS, antibodies, molecularly imprinted polymers
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