MACRO- AND MICROSCALE APPROACH IN THE STUDY ON TRANSPORT PROPERTIES OF REACTIVE AGAROSE HYDROGELS

1 KALINA Michal
Co-authors:
1 SMILEK Jiri 1 ADAMCOVA Zuzana 1 BILKOVA Katerina 1 SEDLACEK Petr
Institutions:
1 Brno University of Technology, Faculty of Chemistry, Materials Research Centre
2 Purkynova 118/464, 612 00, Brno, Czech Republic
Conference:
9th International Conference on Nanomaterials - Research & Application, Hotel Voronez I, Brno, Czech Republic, EU, October 18th - 20th 2017
Proceedings:
Proceedings 9th International Conference on Nanomaterials - Research & Application
Pages:
804-809
ISBN:
978-80-87294-81-9
ISSN:
2694-930X
Published:
8th March 2018
Proceedings of the conference were published in Web of Science and Scopus.
Metrics:
14 views / 8 downloads
Abstract

Hydrogels represent nowadays important material either from scientific point of view, as well as for the applications. This contribution is focused on the study of transport properties of reactive hydrogels based on agarose. This polysaccharide can at certain conditions form hydrogel matrix, which represent ideal carrier matrix for additional substances (e.g. polyelectrolytes). Incorporation of specific modifiers allows tuning the final properties (e.g. reactivity) of these hydrogel in respect to the needs of the application. The experimental part of present work was focused on the observation and quantification of the transport of Rhodamine 6G in individual reactive agarose-based hydrogels. Two basic approaches were used (both based on diffusion processes). Firstly, the simple macroscopic observation of diffusion of Rhodamine 6G from solution into cuvettes containing individual agarose-based reactive hydrogels (diffusion model of constant source) was applied. The second used technique was based on Rhodamine 6G self-diffusion measurement (using the method of fluorescence correlation spectroscopy). Both methods showed to be valuable in deeper description and characterization of the interactions and mobility of selected probe in reactive agarose-based hydrogel matrices. The obtained data from diffusion experiments were correlated with several basic structural characteristics of studied hydrogels (internal pH value, content of water, wettability…) as well as their mechanical properties (mainly rheological). The results indicated that the transport and barrier properties of individual agarose-based hydrogels are significantly affected by charge of the polyelectrolyte, which is incorporated in hydrogels matrix, as well as by its charge density.

Keywords: diffusion, fluorescence correlation spectroscopy, hydrogels, polyelectrolyte, reactivity
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