HYALURONAN BASED NANOPARTICLES FORMED BY ELECTROSTATIC INTERACTIONS

1 JUGL Adam
Co-authors:
1 HEJNÁ Jana 1 PEKAŘ Miloslav
Institution:
1 Materials Research Centre, Faculty of Chemistry, Brno University of Technology, Brno, Czech Republic, xcjugl@fch.vut.cz
Conference:
9th International Conference on Nanomaterials - Research & Application, Hotel Voronez I, Brno, Czech Republic, EU, October 18th - 20th 2017
Proceedings:
Proceedings 9th International Conference on Nanomaterials - Research & Application
Pages:
543-547
ISBN:
978-80-87294-81-9
ISSN:
2694-930X
Published:
8th March 2018
Proceedings of the conference were published in Web of Science and Scopus.
Metrics:
15 views / 14 downloads
Abstract

This work is focused on the preparation and characterization of nanoparticles. Particles were prepared from negatively charged polymer – sodium hyaluronate and oppositely charged polyaminoacid – polyarginine hydrochloride in water and 0.15 M sodium chloride. Due to the composition of nanoparticles from biodegradable materials, particles may be attractive for medical applications. Particles were studied using dynamic light scattering.The second part of this work is focused on study of electrostatic interactions between negatively charged hyaluronan chains and simple amino acids (lysine and arginine) in water. These interactions were studied by means of calorimetry.

Keywords: Hyaluronan, amino acid, polyarginine, nanoparticles, dynamic light scattering, calorimetry
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