OPTIMIZATION OF NANO- AND SUBMICRO-SCALED MESOPOROUS SILICA PARTICLES WITH TUNABLE SURFACE PROPERTIES FOR ADVANCED DRUG DELIVERY

1 Filatova K. O.
Co-authors:
1 Moghaddam M. A. 1 Sedlarik V.
Institution:
1 Centre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Zlin, Czech Republic, EU
Conference:
9th International Conference on Nanomaterials - Research & Application, Hotel Voronez I, Brno, Czech Republic, EU, October 18th - 20th 2017
Proceedings:
Proceedings 9th International Conference on Nanomaterials - Research & Application
Pages:
180-185
ISBN:
978-80-87294-81-9
ISSN:
2694-930X
Published:
8th March 2018
Proceedings of the conference were published in Web of Science and Scopus.
Metrics:
31 views / 12 downloads
Abstract

The Si-based submicro- and nanoparticles were prepared using a template sol-gel approach in the presence of cationic surfactants with different length of alkyl chains and alkaline catalysts that allowed a modulation of pore size and surface area of particles in the synthesis mixture to obtain materials with a wide range of size (25-1000 nm) and variable textural characteristics. Mesoporous materials were prepared with the aim to optimize and adapt different synthetic routs for further use of SP as reservoirs for carrying and advanced delivery of therapeutics.

Keywords: Mesoporous silica particles synthesis, Stöber method, Drug delivery
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