SPRi (Surface Plasmon Resonance Imaging) biosensors are used for detection in real time with advantage of processing large number parallel measurements. Our goal is fast detection of low concentrations proteins. A low concentration testing of proteins in urea or blood serum is needed for clinical practice.This article shows the problems of measuring proteins in real samples of body fluids. The original biochip detecting albumin (HSA - Human serum albumin) was implemented and tested both by standard tests, and by the patient samples.Keywords: optical measurements, surface plasmon resonance, albumin
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