The Lean Six Sigma methodology is a disciplined and logical approach that is used in industrial companies to improve various processes. The essence of improvement is to reduce variability, eliminate defects and eliminate waste, especially in manufacturing processes of which logistics activities are an integral part. This methodology is based primarily on statistical methods, simpler and more complex quality management methods as well as lean management methods. The main importance that adds to the value of the Lean Six Sigma methodology compared to other improvement methodologies is the application of advanced industrial engineering methods and more complex statistical methods and the use of measurable financial indicators to interpret results.The paper focuses on the application of Lean Six Sigma or Six Sigma methodology in industrial practice. The main objective of the paper is to identify and analyze the critical factors of failure of implementation of Lean Six Sigma methodology in industrial enterprises in Slovakia in comparison with enterprises in the world.Keywords: Lean Six Sigma, quality management, process improvement, industrial engineering methods
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