HYDROGELS WITH HYDROPHOBIC NANODOMAINS

1 PEKAŘ Miloslav
Co-authors:
1 JARÁBKOVÁ Sabína 1 SMILEK Jiří 1 MRAVEC Filip
Institution:
1 Brno University of Technology, Faculty of Chemistry, Materials Research Centre, Brno, Czech Republic, EU
Conference:
8th International Conference on Nanomaterials - Research & Application, Hotel Voronez I, Brno, Czech Republic, EU, October 19th - 21st 2016
Proceedings:
Proceedings 8th International Conference on Nanomaterials - Research & Application
Pages:
414-418
ISBN:
978-80-87294-71-0
ISSN:
2694-930X
Published:
17th March 2017
Proceedings of the conference were published in Web of Science and Scopus.
Metrics:
26 views / 2 downloads
Abstract

Ionic interactions between oppositely charged polyelectrolytes and surfactants can - under proper conditions - lead to formation of physical gels. The surfactants form micellar structures enabling to solubilize hydrophobic substances in the otherwise aqueous environment of the gel. Resulting materials can find use in the formulation of delivery systems, e.g. for hydrophobic drugs especially in topical applications. We report on the techniques of preparation of such materials from positively charged polysaccharides (chitosan, cationized dextran) and negatively charged surfactant and on their rheological properties in dependence of their composition.

Keywords: Hydrogels, polyelectrolytes, micelles, nanodomains, surfactants
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