DEVELOPMENT OF NEW BIODEGRADABLE ALLOYS FOR MEDICAL APPLICATIONS

1 MOLČANOVÁ Zuzana
Co-authors:
1 BALLOKOVÁ Beáta 2 ĎURIŠIN Juraj 1,2 ŠUĽOVÁ Katarína 3 ŠULIKOVÁ Michaela 3 LACHOVÁ Andrea 3 LISNICHUK Maksym 1,3 FEJERČÁK Miloš 3 MARTINKOVÁ Slávka 4 MICHALIK Štefan 1,3,5 SAKSL Karel
Institutions:
1 Institut of Materials Research, Slovak Academy of Sciences, Košice, Slovak Republic, EU, molcanova@saske.sk, bballokova@saske.sk, ksulova@saske.sk, milos.fejercak@gmail.com
2 Technical University of Košice, Košice, Slovak Republic, EU, juraj.durisin@tuke.sk
3 Pavol Jozef Šafárik University in Košice, Košice, Slovak Republic, EU, michaela.sulikova1@student.upjs.sk, lachova.ada@gmail.com, slavka.martinkova@gmail.com
4 Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot, United Kingdom,EU still EU, stefan.michalik@diamond.ac.uk
5 Corresponding author. Tel.: +421 55 7922457; Fax: +421 55 7922408. e-mail address: ksaksl@saske.sk
Conference:
28th International Conference on Metallurgy and Materials, Hotel Voronez I, Brno, Czech Republic, EU, May 22nd - 24th 2019
Proceedings:
Proceedings 28th International Conference on Metallurgy and Materials
Pages:
1204-1209
ISBN:
978-80-87294-92-5
ISSN:
2694-9296
Published:
4th November 2019
Proceedings of the conference were published in Web of Science and Scopus.
Metrics:
45 views / 16 downloads
Abstract

In surgery, besides the joint replacements that need permanent prosthesis implantation in the human body, there are many other clinical cases, such as bone fracture, cardiovascular diseases, in which the temporary implant materials are needed. The fixation or mechanical support are there temporarily needed during the healing process of the injured or pathological tissue, and after that, the implants accomplish their mission have no longer function in human body. In this case, biodegradable materials are the optimal choice as these materials do their job while healing and a new tissue forming occur and degrade in the human body thereafter. Amorphous alloys based on magnesium and calcium are nowadays a very perspective group of metallic glasses. We have developed composition series of completely new (not published) ternary Ca-Mg-Au biodegradable alloys with attractive properties in terms of possible future applications (density and elastic modulus comparable to human bones, wide supercooled liquid region etc.). Although the rate of their degradation in physiological solutions is still too fast, these ternary alloys will serve as precursors for design of future highly alloyed systems with tuned dissociation rate in human body.

Keywords: Biodegradable alloys, X-ray diffraction, nanoindentation, alloy dissolution
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